Journal
CEREBRAL CORTEX
Volume 19, Issue 4, Pages 777-785Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cercor/bhn124
Keywords
DT-MRI; middle longitudinal fascicle; segmentation; tractography
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Funding
- NCCIH NIH HHS [P01AT002048-05] Funding Source: Medline
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Experimental and imaging studies in monkeys have outlined various long association fiber bundles within the temporoparietal region. In the present study the trajectory of the middle longitudinal fascicle (MdLF) has been delineated in 4 human subjects using diffusion tensor magnetic resonance imaging segmentation and tractography. The MdLF seems to extend from the inferior parietal lobule (IPL), specifically the angular gyrus, to the temporal pole remaining within the white matter of the superior temporal gyrus (STG). Comparison of the superior longitudinal fascicle II-arcuate fascicle (SLF II-AF) with the MdLF in the same subjects revealed that MdLF is located in a medial and caudal position relative to SLF II-AF and that it extends more rostrally. Given the location of MdLF between the IPL (angular gyrus) and the STG, it is suggested that MdLF could have a role in language and attention functions.
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