Journal
BIOGERONTOLOGY
Volume 3, Issue 1-2, Pages 7-12Publisher
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1015270322517
Keywords
aging; Caenorhabditis elegans; error catastrophe; gerontogene; heritability; hormesis; longevity mutant; programmed aging; review; stress resistance
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Funding
- NATIONAL INSTITUTE ON AGING [R01AG012423, R01AG016219, P01AG008761] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM [K02AA000195] Funding Source: NIH RePORTER
- NIAAA NIH HHS [K02-AA00195] Funding Source: Medline
- NIA NIH HHS [R01-AG12423, R01-AG16219, P01 AG08761] Funding Source: Medline
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This is a personal account of the early days in the genetic analysis of aging when it was difficult to persuade the world that there were genes that specified life prolongation. I describe the situation in 1980 and briefly describe the background of early work on the nematode Caenorhabditis elegans and my role in the revolution in aging research that has occurred in the last 20 years.
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