Journal
JOURNAL OF VIROLOGY
Volume 76, Issue 5, Pages 2548-2550Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.76.5.2548-2550.2002
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Funding
- Wellcome Trust Funding Source: Medline
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We have previously described postentry restriction of murine leukemia virus in mammals. Here we characterize the block in human cells. Restricted infection kinetics are multiple hit at high virus dose, and restriction is abrogated by preexposure to restricted virus. We hypothesize that restricted capsid can titrate out the restriction factor.
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