4.7 Article

Tyrosine 92 of aristolochene synthase directs cyclisation of farnesyl pyrophosphate

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 20, Pages 2384-2385

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b206517g

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A mutant of Aristolochene Synthase (AS), in which Tyr 92 was replaced by Val, produced the alicyclic beta-(E)-farnesene as the major product, indicating that cyclisation of FPP is controlled by Tyr 92 in AS.

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