4.7 Article

Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: formal synthesis of (-)-kainic acid

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 1, Pages 38-39

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b109188c

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Chiral lithium amides deprotonate N-benzyl benzamides enantioselectively, initiating an asymmetric dearomatising cyclisation to enantiomerically enriched isoindolinones.

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