Synthesis of BF2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

The synthesis, spectroscopic characteristics and in vitro cellular uptake properties of a new class of therapeutic window photosensitiser, namely the BF2 chelates of 3,5-diaryl-1H- pyrrol-2-yl-3,5-diarylpyrrol-2-ylidene amines (tetraarylazadipyrromethenes), are described with the aim of developing a novel class of photodynamic therapeutic agents.