Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 18, Pages 2112-2113Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b204920c
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It is demonstrated in this report that the authentic molecular structure of antibiotic varacin is capable of causing DNA-cleavage with high efficiency in the presence of thiols. In addition, it is found that the DNA-cleaving activity by varacin is apparently promoted by its acidic environments.
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