4.7 Article

Enantioselective synthesis and application of the highly fluorescent and environment-sensitive amino acid 6-(2-dimethylaminonaphthoyl) alanine (DANA)

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 17, Pages 1912-1913

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b205224e

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Funding

  1. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [U54GM064346] Funding Source: NIH RePORTER
  2. NIGMS NIH HHS [GM64346] Funding Source: Medline

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6-(2-Dimethylaminonaphthoyl) alanine (DANA) was prepared via an enantioselective synthesis and incorporated into the S-peptide of RNase S establishing the large changes in fluorescence that can occur upon peptide-protein interaction.

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