4.7 Article

A hydrocarbon anchored peptide that forms a chloride- selective channel in liposomes

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 8, Pages 840-841

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b200126h

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The heptapeptide sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly, when anchored to diglycolic acid derived (C18H37)(2)NCOCH2OCH2COOH, forms chloride-selective ion channels in phospholipid liposomes but the related heptapeptide GlyGly-Gly-Leu-Gly-Gly-Gly, and tripeptide Gly-Gly-Gly do not.

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