4.7 Article

One-pot synthesis of hydrogen phosphonate derivatives of d4T and AZT

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 20, Pages 2414-2415

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b207657h

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A simple and one-pot route for the synthesis of d4T or AZT hydrogen phosphonate derivatives via reaction of d4T or AZT with phosphorus trichloride, then alcoholysis and dealkylation in the presence of the corresponding alcohol is described.

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