Viscoelastic properties of cross-linked polyvinyl alcohol and surface-oxidized cellulose whisker hydrogels

Reinforcement of polyvinyl alcohol (PVA) hydrogels was achieved by direct chemical cross-linking of surface modified microcrystalline cellulose (MCC) whiskers with PVA. In order to produce hydrogels, the MCC whiskers were first obtained by TEMPO-mediated oxidation of the cellulose substrate and ultrasonication followed by direct cross-linking to PVA (Mw 98,000) via forming acetal bonds and freeze-thawing. The viscoelastic properties of the produced hydrogels were clearly improved following the chemical cross-linking, featuring values for viscous and elastic moduli G' and GaEuro(3) on the order of 10 kPa, which is particularly interesting for biomedical orthopedic applications.