Synthesis and characterization of antibacterial semi-interpenetrating carboxymethyl chitosan/poly (acrylonitrile) hydrogels

Blend hydrogels composed of carboxymethyl chitosan (CMCh) and poly (acrylonitrile) (PAN) were synthesized via crosslinking method. Several analyses were made to investigate both physical and thermal properties of CMCh/PAN hydrogels like; FTIR, scanning electron microscope, XRD and thermogravimetric analysis (TGA). TGA results showed that CMCh/PAN hydrogels are thermally more stable than CMCh and their thermal stability increases as PAN content increases in the hydrogel. Moreover, the swelling behavior of CMCh/PAN hydrogels was studied in different buffer solutions. It was found that CMCh/PAN hydrogels swell much more than PAN especially at pH 9. The hydrogels sorption for different dyestuff and various metal ions like; Cu2+, Cd2+ and Co2+ were also studied. In this work, antibacterial characteristic of hydrogels was mainly investigated towards Escherichia coli (E. coli) as a serious disease-leading bacterium. All tested hydrogels have clearly presented good antibacterial activity as CMCh content increases in the hydrogels.