4.3 Article

1,8-diazabicyclo[5.4.0]undec-7-ene (DBU): A powerful catalyst for the Michael addition reaction of beta-ketoesters to acrylates and enones

Journal

SYNTHETIC COMMUNICATIONS
Volume 32, Issue 21, Pages 3247-3254

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1081/SCC-120014028

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The Michael addition reaction of 1,3-dicarbonyl compounds and enones was carried out in the presence of a catalytic amount of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in ethanol under the mild reaction condition furnished Michael adducts in excellent yield.

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