Journal
PHYTOCHEMISTRY
Volume 59, Issue 6, Pages 649-654Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9422(02)00023-7
Keywords
Prangos pabularia; Umbelliferae; coumarins; gamma-pyrone derivatives; antibacterial activity; cytokine release
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The n-hexane and ethyl acetate extracts of the stems and the ethyl acetate extracts of roots from Prangos pabularia afforded an gamma-pyrone derivative and furanocoumarin derivatives with three glucose and gamma-pyrone (pabularin A, B and C), along with 26 previously known compounds (18 cournarins, six terpenoids and two glycosides). Their structures were established on the basis of spectroscopic studies. Of these, 16 coumarin derivatives isolated from P. pabularia were tested for antibacterial activity and inhibition of cytokine release. (C) 2002 Elsevier Science Ltd. All rights reserved.
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