3.8 Article

Total synthesis of naamine C and pyronaamidine, antitumor marine imidazole alkaloids

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ROYAL SOC CHEMISTRY
DOI: 10.1039/b200845a

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The first total synthesis of naamine C and pyronaamidine, highly substituted and cytotoxic imidazole marine alkaloids of a certain kind of sponge, was achieved through an eight-step reaction starting from 1-methyl-2-phenylthio-1H-imidazole.

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