Journal
MUSCLE & NERVE
Volume 25, Issue 3, Pages 445-447Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mus.10050
Keywords
motor neuron disease; motor unit number estimation (MUNE); spinal muscular atrophy (SMA)
Categories
Funding
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [R01HD054599] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR RESEARCH RESOURCES [UL1RR025764] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R21NS041634] Funding Source: NIH RePORTER
- NCRR NIH HHS [UL1 RR025764] Funding Source: Medline
- NICHD NIH HHS [R01 HD054599] Funding Source: Medline
- NINDS NIH HHS [NS41634-01] Funding Source: Medline
Ask authors/readers for more resources
Spinal muscular atrophy (SMA) is a disease of lower motor neurons. Motor unit number estimation (MUNE) is an electrophysiologic method to estimate the number of motor neurons innervating a muscle group. We applied the multiple point stimulation technique to the ulnar nerve-hypothenar muscle group to study lower motor neuron loss in 14 SMA subjects, including those presymptomatic, and varying from newborn through 45 years of age. Preliminary data support the value of MUNE to help understand the time course of motor neuron loss in SMA. (C) 2002 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
