Journal
SURGERY TODAY
Volume 32, Issue 8, Pages 742-746Publisher
SPRINGER
DOI: 10.1007/s005950200140
Keywords
combined hepatocellular-cholangiocarcinoma; hepatectomy; recurrence
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Because of the low incidence rate of combined hepato-cellular-cholangiocarcinoma (combined HCC-CC), the clinicopathological features of a recurrent tumor of this disease remain to be elucidated. We describe a 47-year-old Japanese woman with a 5-cm diameter mass lesion in the liver. A hepatectomy and dissection of the local lymph nodes were performed and a histological examination of the resected specimen showed combined HCC-CC. After a follow-up of 15 months, intrahepatic recurrence was observed. and a hepatectomy was performed again followed by hepatic arterial infusion chemotherapy. A histological examination revealed that the recurrent tumors consisted of only cholangioacarcinoma. A disease-free survival was obtained for about 7 years after the recurrence. To improve the poor prognosis of combined HCC-CC. clinicopathological features of this disease and the therapy selection for recurrent tumors should be discussed.
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