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Modelling viral and immune system dynamics

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NATURE REVIEWS IMMUNOLOGY
Volume 2, Issue 1, Pages 28-36

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NATURE PUBLISHING GROUP
DOI: 10.1038/nri700

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During the past 6 years, there have been substantial advances in our understanding of human immunodeficiency virus I and other viruses, such as hepatitis B virus and hepatitis C virus, that cause chronic infection. The use of mathematical modelling to interpret experimental results has made a significant contribution to this field. Mathematical modelling is also improving our understanding of T-cell dynamics and the quantitative events that underlie the immune response to pathogens.

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