Journal
JOURNAL OF PHARMACY AND PHARMACOLOGY
Volume 54, Issue 3, Pages 435-439Publisher
OXFORD UNIV PRESS
DOI: 10.1211/0022357021778510
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Goldenseal (Hydrastis canadensis L.) has emerged as one of the top ten herbal supplements on the worldwide market. A rapid, simple and validated high performance liquid chromatographic method, with photodiode array detection, has been developed for the analysis of commercial Goldenseal products. Samples were treated by sonication with acidified methanol/water. The method was validated for LOD, LOQ, linearity, reproducibility and recovery with good results.
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