Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 21, Issue 3, Pages 166-174Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0165-9936(02)00304-7
Keywords
nucleic acids; ohgonucleotides; ion-pair reversed-phase liquid chromatography; monolithic capillary columns; electrospray ionization-mass spectrometry (ESI-MS)
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Monolithic capillary columns prepared by copolymerization of styrene and divinylbenzene inside a 200 mum i.d. fused silica capillary allow the rapid and highly efficient separation of single- and double-stranded DNA by ion-pair reversed-phase high-performance liquid chromatography. Hyphenation to electrospray ionization-mass spectrometry can be readily achieved. (C) 2002 Published by Elsevier Science B.V. All rights reserved.
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