Journal
STRUCTURE
Volume 10, Issue 3, Pages 285-288Publisher
CELL PRESS
DOI: 10.1016/S0969-2126(02)00732-3
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Characterization of the apoptosome by cryo-EM reveals a wheel-shaped heptameric assembly involving Apaf-1 and cytochrome c. This structure provides a framework for understanding the activation mechanisms of caspase-9, an important initiator caspase in apoptosis.
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