Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 71, Issue 20, Pages 3939-3950Publisher
SPRINGER BASEL AG
DOI: 10.1007/s00018-014-1662-8
Keywords
Tyrosine nitration; Cell death; Reactive nitrogen species; Peroxynitrite; Nitrated Hsp90
Categories
Funding
- Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida
- National Institute of Health (NIH) [NS36761]
- Burke Medical Research Institute Goldsmith Fellowship
Ask authors/readers for more resources
Nitrotyrosine is used as a marker for the production of peroxynitrite and other reactive nitrogen species. For over 20 years the presence of nitrotyrosine was associated with cell death in multiple pathologies. Filling the gap between correlation and causality has proven to be a difficult task. Here, we discuss the evidence supporting tyrosine nitration as a specific posttranslational modification participating in the induction of cell death signaling pathways.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
