4.7 Review

Interplay between genetic and epigenetic factors governs common fragile site instability in cancer

Related references

Note: Only part of the references are listed.
Review Medicine, Research & Experimental

WW domain-containing oxidoreductase's role in myriad cancers: Clinical significance and future implications

Aliza Gardenswartz et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2014)

Article Biochemistry & Molecular Biology

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

Jacqueline H. Barlow et al.

Article Multidisciplinary Sciences

Replication stress links structural and numerical cancer chromosomal instability

Rebecca A. Burrell et al.

NATURE (2013)

Article Cell Biology

MUS81 promotes common fragile site expression

Songmin Ying et al.

NATURE CELL BIOLOGY (2013)

Review Genetics & Heredity

Common fragile sites: mechanisms of instability revisited

Michelle Debatisse et al.

TRENDS IN GENETICS (2012)

Article Biochemistry & Molecular Biology

Heterochromatin and the DNA damage response: the need to relax

Kendra L. Cann et al.

BIOCHEMISTRY AND CELL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

Assaf C. Bester et al.

Article Biochemistry & Molecular Biology

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

Efrat Ozeri-Galai et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Molecular profiling of common fragile sites in human fibroblasts

Benoit Le Tallec et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

Matilde Murga et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Replication dynamics at common fragile site FRA6E

Elisa Palumbo et al.

CHROMOSOMA (2010)

Article Genetics & Heredity

Fragile sites and chromosome breakpoints in constitutional rearrangements I. Amniocentesis

Frederick Hecht et al.

CLINICAL GENETICS (2010)

Article Genetics & Heredity

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

Martin F. Arlt et al.

DNA REPAIR (2010)

Article Biochemistry & Molecular Biology

Impaired replication dynamics at the FRA3B common fragile site

Aparna Palakodeti et al.

HUMAN MOLECULAR GENETICS (2010)

Article Oncology

Deletion at Fragile Sites Is a Common and Early Event in Barrett's Esophagus

Lisa A. Lai et al.

MOLECULAR CANCER RESEARCH (2010)

Article Multidisciplinary Sciences

Signatures of mutation and selection in the cancer genome

Graham R. Bignell et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells

M. Gandhi et al.

ONCOGENE (2010)

Article Multidisciplinary Sciences

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

R. Scott Hansen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Oncology

Claspin Inhibition Leads to Fragile Site Expression

Maria Luisa Focarelli et al.

GENES CHROMOSOMES & CANCER (2009)

Article Biochemistry & Molecular Biology

Common fragile sites are characterized by histone hypoacetylation

Yanwen Jiang et al.

HUMAN MOLECULAR GENETICS (2009)

Review Genetics & Heredity

Molecular Mechanisms of Human Papillomavirus-Induced Carcinogenesis

Michael Lehoux et al.

PUBLIC HEALTH GENOMICS (2009)

Review Biochemistry & Molecular Biology

Human chromosome fragility

T. Lukusa et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2008)

Article Cell Biology

Replication timing of two human common fragile sites: FRA1H and FRA2G

F. Pelliccia et al.

CYTOGENETIC AND GENOME RESEARCH (2008)

Article Cell Biology

Werner syndrome helicase activity is essential in maintaining fragile site stability

Livia Maria Pirzio et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Molecular parameters of genome instability: Roles of fragile genes at common fragile sites

Flavia Pichiorri et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Interplay between ATM and ATR in the regulation of common fragile site stability

E. Ozeri-Galai et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

Non-transcriptional control of DNA replication by c-Myc

David Dominguez-Sola et al.

NATURE (2007)

Review Oncology

Large common fragile site genes and cancer

David I. Smith et al.

SEMINARS IN CANCER BIOLOGY (2007)

Article Oncology

Relationship between FRA11F and 11q13 gene amplification in oral cancer

Shalini C. Reshmi et al.

GENES CHROMOSOMES & CANCER (2007)

Article Cell Biology

Non-random inactivation of large common fragile site genes in different cancers

S. McAvoy et al.

CYTOGENETIC AND GENOME RESEARCH (2007)

Article Multidisciplinary Sciences

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco et al.

NATURE (2006)

Review Genetics & Heredity

Common fragile sites as targets for chromosome rearrangements

Martin F. Arlt et al.

DNA REPAIR (2006)

Review Genetics & Heredity

Gene amplification in cancer

Donna G. Albertson

TRENDS IN GENETICS (2006)

Article Biochemistry & Molecular Biology

Fragile sites are preferential targets for integrations of MLV vectors in gene therapy

A. C. Bester et al.

GENE THERAPY (2006)

Article Biochemistry & Molecular Biology

Regulation of replication licensing by acetyltransferase Hbo1

M Iizuka et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Oncology

Common chromosomal fragile sites and cancer: Focus on FRA16D

LV O'Keefe et al.

CANCER LETTERS (2006)

Article Multidisciplinary Sciences

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

J Bartkova et al.

NATURE (2005)

Article Oncology

The role of viral integration in the development of cervical cancer

TX Yu et al.

CANCER GENETICS AND CYTOGENETICS (2005)

Article Biochemistry & Molecular Biology

SMC1 involvement in fragile site expression

A Musio et al.

HUMAN MOLECULAR GENETICS (2005)

Article Genetics & Heredity

Chromosomal instability at common fragile sites in Seckel syndrome

AM Casper et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2004)

Article Biochemistry & Molecular Biology

BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function

MF Arlt et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Two breakpoint clusters at fragile site FRA3B form phased nucleosomes

DJ Mulvihill et al.

GENOME RESEARCH (2004)

Article Biochemistry & Molecular Biology

Conservation of aphidicolin-induced fragile sites in Papionini (Primates) species and humans

A Ruiz-Herrera et al.

CHROMOSOME RESEARCH (2004)

Article Oncology

The role of late/slow replication of the FRA16D in common fragile site induction

A Palakodeti et al.

GENES CHROMOSOMES & CANCER (2004)

Article Multidisciplinary Sciences

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

S Hacein-Bey-Abina et al.

SCIENCE (2003)

Article Biochemistry & Molecular Biology

Molecular basis for expression of common and rare fragile sites

E Zlotorynski et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Common fragile sites are preferential targets for HPV16 integrations in cervical tumors

EC Thorland et al.

ONCOGENE (2003)

Article Biochemistry & Molecular Biology

Characterization of the common fragile site FRA9E and its potential role in ovarian cancer

G Callahan et al.

ONCOGENE (2003)

Article Biochemistry & Molecular Biology

ATR regulates fragile site stability

AM Casper et al.

Article Multidisciplinary Sciences

Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

T Shiraishi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability

A Hellman et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)