Journal
FARMACO
Volume 57, Issue 3, Pages 183-187Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/S0014-827X(01)01190-9
Keywords
N-(1-phenyl-4-carbetoxypyrazol-5-yl)-2-iodobenzamides; N-(indazol-3-yl)-2-iodobenzamides; N-(indazol-5-yl)-2-iodobenzamides; antifungal activity
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N-(1-Phenyl-4-carbetoxypyrazol-5-yl)-, N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides 6, with a Benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazin ones 5 with potassium iodide for 1 h in order to study the role on the antifungal activity of the N-substitution with an aromatic heterocyclic system on benzamide moiety. Among the tested iododerivatives, compounds 6d,f,g,h possess interesting activities toward some phytopathogenic fungal strains. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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