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Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
Wenlei Zhuo et al.
LUNG CANCER (2008)
Direct regulation of TWIST by HIF-1α promotes metastasis
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
Twist and p53 reciprocally regulate target genes via direct interaction
M. Shiota et al.
ONCOGENE (2008)
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
Cecilia Sahlgren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck
Nina Zidar et al.
VIRCHOWS ARCHIV (2008)
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients
K. Blechschmidt et al.
BRITISH JOURNAL OF CANCER (2008)
Role of p14ARF in TWIST-mediated senescence in prostate epithelial cells
Wai Kei Kwok et al.
CARCINOGENESIS (2007)
Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias
Cristina A. de Frutos et al.
DEVELOPMENTAL CELL (2007)
The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1
Yongqing Liu et al.
BIOCHEMICAL JOURNAL (2007)
Direct repression of cyclin d1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition
Jakob Mejlvang et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Tumour invasion and metastasis initiated by microRNA 10b in breast cancer
Li Ma et al.
NATURE (2007)
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
Hui-Wen Lo et al.
CANCER RESEARCH (2007)
The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
K. Aigner et al.
ONCOGENE (2007)
Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma
Mikio Terauchi et al.
CLINICAL & EXPERIMENTAL METASTASIS (2007)
Differential regulation of epithelial and mesenchymal markers by δEF1 proteins in epithelial-mesenchymal transition induced by TGF-β
Takuya Shirakihara et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Epithelial to mesenchymal transition: Expression of the regulators snail, slug, and twist in pancreatic cancer
Birgit Hotz et al.
CLINICAL CANCER RESEARCH (2007)
miR-200b mediates post-transcriptional repression of ZFHX1B
Nanna Ronbjerg Christoffersen et al.
RNA (2007)
Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-Driven murine lung cancer
Fatih Ceteci et al.
CANCER CELL (2007)
Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation
Amaya Miquelajauregui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression
Zhou Yang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
Sendurai A. Mani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Upregulation of Twist-1 by NF-κB blocks cytotoxicity induced by chemotherapeutic drugs
Can G. Pham et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma
Barbara A. Frederick et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Upregulation of Twist in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis
Hiu-Fung Yuen et al.
JOURNAL OF CLINICAL PATHOLOGY (2007)
Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells
Xiaomeng Zhang et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Opposing LSD1 complexes function in developmental gene activation and repression programmes
Jianxun Wang et al.
NATURE (2007)
Twist, a novel oncogene is upregulated in pancreatic cancer:: Clinical implication of Twist expression in pancreatic juice
Kenoki Ohuchida et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer
Y. Imamichi et al.
ONCOGENE (2007)
Significance of TWIST and E-cadherin expression in the metastatic progression of prostatic cancer
H-F Yuen et al.
HISTOPATHOLOGY (2007)
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
George Z. Cheng et al.
CANCER RESEARCH (2007)
NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells:: potential involvement of ZEB-1 and ZEB-2
H. L. Chua et al.
ONCOGENE (2007)
Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
S. Hosono et al.
BRITISH JOURNAL OF CANCER (2007)
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells
Christopher T. Capaldo et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
Andrew J. Evans et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Expression and significance of TWIST basic helix-loop-helix protein over-expression in gastric cancer
Yan-Qi Zhang et al.
PATHOLOGY (2007)
Slug is overexpressed in gastric carcinomas and may act synergistically with SIPI and Snail in the down-regulation of E-cadherin
C. Castro Alves et al.
JOURNAL OF PATHOLOGY (2007)
Significance of TWIST expression and its association with E-cadherin in bladder cancer
Zheng Zhang et al.
HUMAN PATHOLOGY (2007)
The Spemann organizer gene, Goosecoid, promotes tumor metastasis
Kimberly A. Hartwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Transforming growth factor-β1 induces epithelial-to-mesenchymal transition and apoptosis via a cell cycle-dependent mechanism
Y. Yang et al.
ONCOGENE (2006)
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis
Patrick W. B. Derksen et al.
CANCER CELL (2006)
The clinical significance of twist expression in nasopharyngeal carcinoma
Li-Bing Song et al.
CANCER LETTERS (2006)
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for snail, slug, and E47 factors in epithelial-mesenchymal transition
Gerna Moreno-Bueno et al.
CANCER RESEARCH (2006)
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
Terence K. Lee et al.
CLINICAL CANCER RESEARCH (2006)
Snail and slug play distinct roles during breast carcinoma progression
Christophe Come et al.
CLINICAL CANCER RESEARCH (2006)
Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa
Ann E. Vernon et al.
DEVELOPMENT (2006)
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
Simone Spaderna et al.
GASTROENTEROLOGY (2006)
Regulation of vimentin by SIP1 in human epithelial breast tumor cells
S. Bindels et al.
ONCOGENE (2006)
Transforming growth factor-β employs HMGA2 to elicit epithelial-mesenchymal transition
Sylvie Thuault et al.
JOURNAL OF CELL BIOLOGY (2006)
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
Anthony D. Yang et al.
CLINICAL CANCER RESEARCH (2006)
TGFβ:: the molecular Jekyll and Hyde of cancer
Brian Bierie et al.
NATURE REVIEWS CANCER (2006)
δEF1 mediates TGF-β signaling in vascular smooth muscle cell differentiation
Go Nishimura et al.
DEVELOPMENTAL CELL (2006)
δEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis
Leo A. Van Grunsven et al.
DEVELOPMENTAL DYNAMICS (2006)
Cyclooxygenase-2-dependent regulation of E-cadherin:: Prostaglandin E2 induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
Mariam Dohadwala et al.
CANCER RESEARCH (2006)
The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers
NS Spoelstra et al.
CANCER RESEARCH (2006)
N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1
NR Alexander et al.
CANCER RESEARCH (2006)
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B
B Krishnamachary et al.
CANCER RESEARCH (2006)
Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells
N Ozturk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
SE Witta et al.
CANCER RESEARCH (2006)
Snail1 transcriptional repressor binds to its own promoter and controls its expression
Sandra Peiro et al.
NUCLEIC ACIDS RESEARCH (2006)
Twist expression predicts poor clinical outcome of patients with clear cell carcinoma of the ovary
Hiroaki Kajiyama et al.
ONCOLOGY (2006)
Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
RL Yauch et al.
CLINICAL CANCER RESEARCH (2005)
Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer
Y Mironchik et al.
CANCER RESEARCH (2005)
Transcription repressor Slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma
JY Shih et al.
CLINICAL CANCER RESEARCH (2005)
Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas
N Entz-Werlé et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
WS Wu et al.
CELL (2005)
δEF1 repressor controls selectively p53 family members during differentiation
G Fontemaggi et al.
ONCOGENE (2005)
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin
JY Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
S Thomson et al.
CANCER RESEARCH (2005)
A molecular role for lysyl oxidase-like 2 enzyme in Snail regulation and tumor progression
H Peinado et al.
EMBO JOURNAL (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
The transcriptional repressor snail promotes mammary tumor recurrence
SE Moody et al.
CANCER CELL (2005)
Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
WK Kwok et al.
CANCER RESEARCH (2005)
Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
TA Martin et al.
ANNALS OF SURGICAL ONCOLOGY (2005)
Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells
MK Tripathi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Snail, slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
S Elloul et al.
CANCER (2005)
Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities
BA Firulli et al.
NATURE GENETICS (2005)
The transcriptional repressor SNAIL is overexpressed in human colon cancer
HK Roy et al.
DIGESTIVE DISEASES AND SCIENCES (2005)
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
C Vandewalle et al.
NUCLEIC ACIDS RESEARCH (2005)
Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells
XH Wang et al.
ONCOGENE (2004)
β-catenin activates a coordinated expression of the proinvasive factors laminin-5 γ2 chain and MT1-MMP in colorectal carcinomas
F Hlubek et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
HG Pálmer et al.
NATURE MEDICINE (2004)
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
M Kajita et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Snail regulates p21WAN/CIP1 expression in cooperation with E2A and twist
E Takahashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells
S Valsesia-Wittmann et al.
CANCER CELL (2004)
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
J Yang et al.
CELL (2004)
Induction of stem cell factor/c-Kit/Slug signal transduction in multidrug-resistant malignant mesothelioma cells
A Catalano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
H Peinado et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo
H Peinado et al.
JOURNAL OF CELL SCIENCE (2004)
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial-mesenchymal transition
BHP Zhou et al.
NATURE CELL BIOLOGY (2004)
Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
S Yamashita et al.
NATURE (2004)
Snail blocks the cell cycle and confers resistance to cell death
S Vega et al.
GENES & DEVELOPMENT (2004)
Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation
GJ Sheng et al.
CELL (2003)
Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin
LA van Grunsven et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor
D Domínguez et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway
AA Postigo
EMBO JOURNAL (2003)
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
AA Postigo et al.
EMBO JOURNAL (2003)
Coordinated histone modifications mediated by a CtBP co-repressor complex
YJ Shi et al.
NATURE (2003)
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions:: a comparison with Snail and E47 repressors
V Bolós et al.
JOURNAL OF CELL SCIENCE (2003)
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-κB activity
D Sosic et al.
CELL (2003)
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer
E Rosivatz et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
S Guaita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cell-specific phosphorylation of Zfhep transcription factor
ME Costantino et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
MJ Blanco et al.
ONCOGENE (2002)
Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells
JK Richer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
T Brabletz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
MA Pérez-Moreno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
J Comijn et al.
MOLECULAR CELL (2001)
Tip60 is a cell-type-specific transcriptional regulator
F Hlubek et al.
JOURNAL OF BIOCHEMISTRY (2001)
Evidence for a function of CtBP in epithelial gene regulation and anoikis
ML Grooteclaes et al.
ONCOGENE (2000)
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors
AA Postigo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
E Batlle et al.
NATURE CELL BIOLOGY (2000)
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