Journal
PHARMACOPSYCHIATRY
Volume 35, Issue 1, Pages 33-34Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2002-19836
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We reviewed the available literature on the efficacy of a novel anticonvulsant, Tiagabine (TGB), in the treatment of bipolar disorder. Study results indicate that TGB does not represent a valid option in acute mania due its required slow, progressive titration. More rapid titration schemes may lead to severe complications. TGB may be an option as an adjunct long-term treatment approach in refractory patients, but further studies are clearly needed to support this.
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