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Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase
ACB Lim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
R Kitagawa et al.
GENES & DEVELOPMENT (2004)
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
K Ito et al.
NATURE (2004)
The Mre11 complex is required for ATM activation and the G2/M checkpoint
CT Carson et al.
EMBO JOURNAL (2003)
Sequential modification of NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress
TT Huang et al.
CELL (2003)
Requirement of the MRN complex for ATM activation by DNA damage
T Uziel et al.
EMBO JOURNAL (2003)
DNA replication: a complex matter
I Frouin et al.
EMBO REPORTS (2003)
Electron microscopy and 3D reconstructions reveal that human ATM kinase uses an arm-like domain to clamp around double-stranded DNA
O Llorca et al.
ONCOGENE (2003)
Novel localization of the DNA-PK complex in lipid rafts - A putative role in the signal transduction pathway of the ionizing radiation response
H Lucero et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Characteristics of γ-H2AX foci at DNA double strand breaks sites
DR Pilch et al.
BIOCHEMISTRY AND CELL BIOLOGY (2003)
A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome
AR Meetei et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
ATP activates ataxia-telangiectasia mutated (ATM) in vitro -: Importance of autophosphorylation
S Kozlov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
CJ Bakkenist et al.
NATURE (2003)
The ATRs, ATMs, and TORs are giant HEAT repeat proteins
J Perry et al.
CELL (2003)
Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein
A Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A structural characterization of in situ chromatin on cell lines isolated from patients affected by ataxia telangiectasia
M Grattarola et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2003)
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM
H Beamish et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Neocarzinostatin induces Mre11 phosphorylation and focus formation through an ATM- and NBS1-dependent mechanism
SSF Yuan et al.
TOXICOLOGY (2002)
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
KP Hopfner et al.
NATURE (2002)
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
DC Schultz et al.
GENES & DEVELOPMENT (2002)
ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage
A Barzilai et al.
DNA REPAIR (2002)
ATM function and telomere stability
TK Pandita
ONCOGENE (2002)
When repair meets chromatin - First in series on chromatin dynamics
CM Green et al.
EMBO REPORTS (2002)
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
PT Yazdi et al.
GENES & DEVELOPMENT (2002)
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
J Falck et al.
NATURE GENETICS (2002)
Human Rad50/Mre11 is a flexible complex that can tether DNA ends
M de Jager et al.
MOLECULAR CELL (2001)
TATA binding protein-associated CK2 transduces DNA damage, signals to the RNA polymerase III transcriptional machinery
A Ghavidel et al.
CELL (2001)
Chk2 activation dependence on Nbs1 after DNA damage
G Buscemi et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
VM Macaulay et al.
ONCOGENE (2001)
Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase α (PI3Kα) -: Functions of lipid kinase-deficient PI3Kα in signaling
L Pirola et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
KP Hopfner et al.
CELL (2001)
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
D Durocher et al.
CURRENT OPINION IN CELL BIOLOGY (2001)
Ataxia telangiectasia mutated is essential during adult neurogenesis
DR Allen et al.
GENES & DEVELOPMENT (2001)
Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization
A Desai-Mehta et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
S Peretz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1
DM Keller et al.
MOLECULAR CELL (2001)
Participation of ATM in insulin signalling through phosphorylation of eIf-4E-binding protein 1
DQ Yang et al.
NATURE CELL BIOLOGY (2000)
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
XD Zhu et al.
NATURE GENETICS (2000)
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
KP Hopfner et al.
CELL (2000)
FAT: a novel domain in PIK-related kinases
R Bosotti et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Purification and characterization of ATM from human placenta - A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase
DW Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
C Barlow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: Direct chromoshadow domain-KAP-1 corepressor interaction is essential
MS Lechner et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro
T Takahashi et al.
GENES TO CELLS (2000)
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