Journal
MICROBES AND INFECTION
Volume 4, Issue 1, Pages 75-82Publisher
ELSEVIER
DOI: 10.1016/S1286-4579(01)01512-X
Keywords
Salmonella; type III secretion; needle complex
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Funding
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI041069] Funding Source: NIH RePORTER
- NIAID NIH HHS [R01 AI41069] Funding Source: Medline
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The type III secretion needle complex (NC) of Salmonella typhimurium is a complex secretory system that functions to translocate virulence proteins into eukaryotic cells. Evolutionarily it is related to bacterial flagella. Assembly of the NC occurs through ordered secretion, polymerization, and assembly, and requires the coordinated expression and association of over 20 different proteins. Recent progress in the understanding of the assembly and architecture of the NC is reviewed. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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