Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 67, Issue 24, Pages 4197-4211Publisher
SPRINGER BASEL AG
DOI: 10.1007/s00018-010-0498-0
Keywords
Osteoarthritis; Cartilage; Cartilage repair; Disease modifying drugs
Categories
Ask authors/readers for more resources
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most prominent type of arthritis encountered in all countries. Although great efforts have been made to investigate cartilage biology and osteoarthritis pathology, the treatment has lagged behind that of other arthritides, as there is a lack of effective disease-modifying therapies. Numerous approaches for dealing with cartilage degradation have been tried, but enjoyed very little success to develop approved OA treatments with not only symptomatic improvement but also structure-modifying effect. In this review we discuss the most recent findings regarding the regulation of cartilage biology and pathology and highlight their potential therapeutic values.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available