4.5 Article

A novel antibiotic CJ-17,572 from a fungus, Pezicula sp.

Journal

JOURNAL OF ANTIBIOTICS
Volume 55, Issue 1, Pages 19-24

Publisher

JAPAN ANTIBIOT RES ASSN
DOI: 10.7164/antibiotics.55.19

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A new antibiotic, CJ-17,572 (I) was isolated from the fermentation broth of a fungus Pezicula sp. CL11877. The structure of I was determined to be a new equisetin derivative by spectroscopic analyses. The compound inhibits the growth of multi-drug resistant Staphylococcus aureus and Enterococcus faecalis with IC(50)s of 10 and 20 mug/ml, respectively.

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