4.8 Review

Advancing the field of drug delivery: Taking aim at cancer

Journal

CANCER CELL
Volume 4, Issue 5, Pages 337-341

Publisher

CELL PRESS
DOI: 10.1016/S1535-6108(03)00276-9

Keywords

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Funding

  1. NCCIH NIH HHS [R01AT00650] Funding Source: Medline
  2. NCI NIH HHS [CA83106, CA52857, 2P01CA455] Funding Source: Medline
  3. NATIONAL CANCER INSTITUTE [U01CA052857, R01CA083106, U19CA052857] Funding Source: NIH RePORTER
  4. NATIONAL CENTER FOR COMPLEMENTARY &ALTERNATIVE MEDICINE [R01AT000650] Funding Source: NIH RePORTER

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Drug delivery systems for cancer therapeutics have now been used by millions of patients and have resulted in the creation of new therapies as well as significantly improving existing ones. Here we discuss a number of the drug delivery systems that have been approved by regulatory authorities and that are currently in clinical use, such as controlled delivery of cancer therapeutics, local chemotherapy, polymer drug conjugates, liposomal systems, and transdermal drug delivery patches. The next generation of smart drug delivery approaches such as controlled release microchips are discussed as are some of the future challenges and directions in this field.

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