Journal
TRENDS IN BIOTECHNOLOGY
Volume 21, Issue 12, Pages 556-562Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2003.10.005
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Novel peptide therapeutics are increasingly making their way into clinical application. Indeed, certain naturally derived peptides have been successful drugs for many years. With the advent of large biological and synthetic peptide libraries and high-throughput screening, many promising candidates could soon be added to the list of peptides under development. These advances have introduced new strategies for the administration of peptide drugs and improvements of clearance half-lives in vivo. Despite the potential obstacles that remain, peptide therapeutics are poised to play a significant role in the treatment of diseases ranging from Alzheimer's disease to cancer.
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