4.6 Article

Ubiquitin and synaptic dysfunction: ataxic mice highlight new common themes in neurological disease

Journal

TRENDS IN NEUROSCIENCES
Volume 26, Issue 1, Pages 4-7

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0166-2236(02)00013-9

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The gene responsible for the neurological symptoms in ataxia mice has been identified and shown to encode a ubiquitin-specific protease. This study reveals new links between ubiquitination, synapse function and neurological disease.

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