4.7 Article

Synthesis of aza mono, bi and tricyclic compounds. Evaluation of their anti MDR activity

Journal

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 38, Issue 1, Pages 19-26

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S0223-5234(02)01422-8

Keywords

P-gp inhibitors; acridinic compounds; pyridoquinolines

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Anti MDR activity of a series of acridine, pyridoquinoline, quinoline and pyridine analogous amines was evaluated. Interesting activity is displayed by tricyclic compounds. Besides ring size, influence of the side chain was studied. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

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