Journal
TRAFFIC
Volume 4, Issue 11, Pages 717-723Publisher
BLACKWELL MUNKSGAARD
DOI: 10.1034/j.1600-0854.2003.00130.x
Keywords
Ca2+ entry; Ca2+ waves; capacitative; caveolae; caveolin; eNOS; signal transduction; store-operated Ca2+ entry
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The correct spatial and temporal control of Ca2+ signaling is essential for such cellular activities as fertilization, secretion, motility, and cell division. There has been a long-standing interest in the role of caveolae in regulating intracellular Ca2+ concentration. In this review we provide an updated view of how caveolae may regulate both Ca2+ entry into cells and Ca2+-dependent signal transduction.
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