Journal
CELL STEM CELL
Volume 15, Issue 5, Pages 537-538Publisher
CELL PRESS
DOI: 10.1016/j.stem.2014.10.008
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Funding
- Fight for Sight [1351/52] Funding Source: researchfish
- Great Ormond Street Hospital Childrens Charity [V1257] Funding Source: researchfish
- Medical Research Council [G0901550] Funding Source: researchfish
- Rosetrees Trust [M257] Funding Source: researchfish
- MRC [G0901550] Funding Source: UKRI
- Medical Research Council [G0901550] Funding Source: Medline
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Many untreatable blinding diseases involve degeneration of retinal pigmented epithelial (RPE) cells, which has prompted exploration of the therapeutic potential of human-pluripotent-stem-cell-derived RPE. The first safety trials reported in The Lancet of embryonic-stem-cell-derived RPE cell transplants indicate no serious adverse outcomes and encourage further investigation.
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