4.7 Editorial Material

ESC-Derived Retinal Pigmented Epithelial Cell Transplants in Patients: So Far, So Good

Journal

CELL STEM CELL
Volume 15, Issue 5, Pages 537-538

Publisher

CELL PRESS
DOI: 10.1016/j.stem.2014.10.008

Keywords

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Funding

  1. Fight for Sight [1351/52] Funding Source: researchfish
  2. Great Ormond Street Hospital Childrens Charity [V1257] Funding Source: researchfish
  3. Medical Research Council [G0901550] Funding Source: researchfish
  4. Rosetrees Trust [M257] Funding Source: researchfish
  5. MRC [G0901550] Funding Source: UKRI
  6. Medical Research Council [G0901550] Funding Source: Medline

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Many untreatable blinding diseases involve degeneration of retinal pigmented epithelial (RPE) cells, which has prompted exploration of the therapeutic potential of human-pluripotent-stem-cell-derived RPE. The first safety trials reported in The Lancet of embryonic-stem-cell-derived RPE cell transplants indicate no serious adverse outcomes and encourage further investigation.

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