Journal
TRENDS IN CELL BIOLOGY
Volume 13, Issue 1, Pages 32-42Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0962-8924(02)00008-9
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Palmitoylation is one of the most frequent post-translational modifications found on proteins. It contributes to membrane association, protein sorting and many other processes. Through its reversibility, palmitoylation also provides mechanisms to regulate the functional activities of integral and peripheral membrane proteins. Here we discuss evidence that proteins can be palmitoylated at different locations in the cell, how targeting to these locations might be directed, and aspects of the proposed functions of palmitoylation.
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