4.7 Editorial Material

A Call to Standardize Teratoma Assays Used to Define Human Pluripotent Cell Lines

Journal

CELL STEM CELL
Volume 6, Issue 5, Pages 412-414

Publisher

CELL PRESS
DOI: 10.1016/j.stem.2010.04.009

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Funding

  1. Else Kroner-Fresenius-Stiftung
  2. California Institute of Regenerative Medicine
  3. NIH
  4. Bill and Melinda Gates Foundation
  5. O'Keeffe Foundation

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The teratoma assay is the gold standard for documenting pluripotency of human stem cells. However, reports of new human ESC and iPSC lines vary widely in both methods and analysis of teratoma data. We call for consensus standards to be established to make this assay worthy of its golden status.

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