Journal
CELL STEM CELL
Volume 5, Issue 1, Pages 6-8Publisher
CELL PRESS
DOI: 10.1016/j.stem.2009.06.006
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Stem cells age, but the underlying mechanisms remain unclear. In a recent issue of Cell, Inomata and colleagues (2009) show that DNA damage, a prime suspect in stem cell aging, causes graying and loss of melanocyte stem cells by inducing premature differentiation, without inducing apoptosis or senescence.
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