4.7 Editorial Material

TGFβ and SMADs talk to NANOG in human embryonic stem cells

Journal

CELL STEM CELL
Volume 3, Issue 2, Pages 127-128

Publisher

CELL PRESS
DOI: 10.1016/j.stem.2008.07.011

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The TGF beta/activin signaling pathway is important for the maintenance of human embryonic stem cells. In this issue of Cell Stem Cell, Xu et al. (2008) show that this pathway upregulates the expression of a key pluripotency gene NANOG through SMAD2/3.

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