Journal
TRENDS IN CARDIOVASCULAR MEDICINE
Volume 13, Issue 8, Pages 326-330Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2003.08.003
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Funding
- NHLBI NIH HHS [1P50 HL52319] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [P50HL052319] Funding Source: NIH RePORTER
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Currently, device therapy with implantable cardioverter-defibrillators is the only proven effective therapy for sudden cardiac death. However, new insights into the mechanisms of ventricular fibrillation, particularly the role of dynamic factors that cause wave instability, are providing conceptual advances toward developing effective new pharmacotherapy.
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