Journal
CELL METABOLISM
Volume 18, Issue 2, Pages 153-161Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2013.05.017
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Funding
- NIDDK NIH HHS [R01 DK056084, P30 DK026743, P30 DK063720] Funding Source: Medline
- NIGMS NIH HHS [R01 GM097194, R01 GM099844] Funding Source: Medline
- Austrian Science Fund (FWF) [F 3002, Z 136] Funding Source: researchfish
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Cancer cells often have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.
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