Journal
CELL METABOLISM
Volume 18, Issue 4, Pages 461-462Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2013.09.011
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- NIA NIH HHS [R01 AG020255] Funding Source: Medline
- NIDDK NIH HHS [R01 DK111211] Funding Source: Medline
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Increased accumulation of adipose tissue macrophages in obesity propagates chronic inflammation that is closely associated with insulin resistance and type 2 diabetes. Semaphorin 3E, a guidance molecule for neurons, takes on a new role in obesity by directing the recruitment of macrophages in visceral adipose tissue (Shimizu et al., 2013).
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