Journal
CELL METABOLISM
Volume 15, Issue 4, Pages 432-437Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2011.11.013
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Funding
- BioMedical Research Council
- Agency for Science, Technology, and Research (A*STAR), Singapore
- European Commission
- Italian Association for Cancer Research
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Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.
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