Journal
CELL METABOLISM
Volume 15, Issue 5, Pages 570-573Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2012.03.004
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Funding
- NIH [DK056084]
- J. David Gladstone Institutes
- Austrian Science Fund (FWF) [F 3002, Z 136] Funding Source: researchfish
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Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.
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