Journal
AUTOIMMUNITY REVIEWS
Volume 2, Issue 1, Pages 1-7Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S1568-9972(02)00103-9
Keywords
primary biliary cirrhosis; transplantation; recurrent disease
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Liver transplantation is now the accepted treatment for patients with end-stage disease or intractable symptoms. The success rate is high. Those grafted for PBC are at greater risk of developing acute and chronic rejection and are less likely to be weaned from immunosuppression. Following transplantation, AMA persist and histological features of PBC may be seen in the allograft, in up to 50% by 10 years. (C) 2002 Elsevier Science B.V. All rights reserved.
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