Journal
CELL METABOLISM
Volume 13, Issue 1, Pages 7-8Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2010.12.016
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Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated) are strongly associated with obesity susceptibility. A recent study in Nature Genetics (Church et al., 2010) demonstrates that mice overexpressing fto exhibit a dose-dependent increase in body weight, confirming a role for FTO in the development of obesity.
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