Journal
CELL METABOLISM
Volume 11, Issue 5, Pages 345-346Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2010.04.012
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Nutritional and genetic factors alter the intestinal microflora, predisposing individuals toward metabolic syndrome. Gewirtz and coworkers (Vijay-Kumar et al., 2010), employing Toll-like receptor 5 null mice, present evidence for a direct relationship between malfunction of the innate immune system, changes in gut microbiota composition, and development of metabolic syndrome.
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