Journal
CELL METABOLISM
Volume 9, Issue 3, Pages 215-216Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2009.02.001
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Fructose is a highly lipogenic dietary nutrient that has been implicated in the pathogenesis of hyperlipidemia and insulin resistance. In this issue, Nagai et al. (2009) provide in vivo evidence that pinpoints transcriptional coactivator PGC-1 beta as a key factor in mediating the metabolic response to fructose intake.
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