Journal
CELL METABOLISM
Volume 8, Issue 1, Pages 4-5Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2008.06.004
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Funding
- NIA NIH HHS [P50 AG005136, P50 AG005136-25] Funding Source: Medline
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Sirtuins are known to slow aging in simple eukaryotes; however, viewing mammalian sirtuins as antiaging proteins may be overly simplistic. In this issue of Cell Metabolism, Li et al. (2008) provide evidence that SirT1 has properties consistent with both pro- and antiaging functions in mice.
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